Activities of Sordarins in Experimental Models of Candidiasis, Aspergillosis, and Pneumocystosis

av Martinez, Antonio, Aviles, Pablo, Jimenez, Elena, Caballero, Jesus, Gargallo-Viola, Domingo
Publicerad 2000

In Vitro Pharmacodynamic Parameters of Sordarin Derivatives in Comparison with Those of Marketed Compounds against Pneumocystis carinii Isolated from Rats

av Aviles, Pablo, Aliouat, El-Moukhtar, Martinez, Antonio, Dei-Cas, Eduardo, Herreros, Esperanza, Dujardin, Lucien, Gargallo-Viola, Domingo
Publicerad 2000

c-Jun N-Terminal Kinase Phosphorylation Is a Biomarker of Plitidepsin Activity

av Muñoz-Alonso, María J., Álvarez, Enrique, Guillén-Navarro, María José, Pollán, Marina, Avilés, Pablo, Galmarini, Carlos M., Muñoz, Alberto
Publicerad 2013

Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis

av Moneo, Victoria, Serelde, Beatriz G, Blanco-Aparicio, Carmen, Diaz-Uriarte, Ramon, Avilés, Pablo, Santamaría, Gemma, Tercero, Juan C, Cuevas, Carmen, Carnero, Amancio
Publicerad 2014

Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors

av Wang, Yannick, Wozniak, Agnieszka, Wellens, Jasmien, Gebreyohannes, Yemarshet K., Guillén, Maria Jose, Avilés, Pablo M., Debiec-Rychter, Maria, Sciot, Raf, Schöffski, Patrick
I publikationen Transl Oncol (2020)

Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells

av Galmarini, Carlos M., Martin, Maud, Bouchet, Benjamin Pierre, Guillen-Navarro, María José, Martínez-Diez, Marta, Martinez-Leal, Juan Fernando, Akhmanova, Anna, Aviles, Pablo
I publikationen BMC Cancer (2018)

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models

av Céspedes, María Virtudes, Guillén, María José, López-Casas, Pedro Pablo, Sarno, Francesca, Gallardo, Alberto, Álamo, Patricia, Cuevas, Carmen, Hidalgo, Manuel, Galmarini, Carlos María, Allavena, Paola, Avilés, Pablo, Mangues, Ramón
I publikationen Dis Model Mech (2016)

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110

av Domínguez, Juan Manuel, Pérez-Chacón, Gema, Guillén, María José, Muñoz-Alonso, María José, Somovilla-Crespo, Beatriz, Cibrián, Danay, Acosta-Iborra, Bárbara, Adrados, Magdalena, Muñoz-Calleja, Cecilia, Cuevas, Carmen, Sánchez-Madrid, Francisco, Avilés, Pablo, Zapata, Juan M.
I publikationen J Hematol Oncol (2020)

Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone

av López-Iglesias, Ana-Alicia, González-Méndez, Lorena, San-Segundo, Laura, Herrero, Ana B., Hernández-García, Susana, Martín-Sánchez, Montserrat, Gutiérrez, Norma C., Paíno, Teresa, Avilés, Pablo, Mateos, María-Victoria, San-Miguel, Jesús F., Garayoa, Mercedes, Ocio, Enrique M.
I publikationen Haematologica (2017)

Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response

av Colado, Enrique, Paíno, Teresa, Maiso, Patricia, Ocio, Enrique M., Chen, Xi, Álvarez-Fernández, Stela, Gutiérrez, Norma C., Martín-Sánchez, Jesús, Flores-Montero, Juan, San Segundo, Laura, Garayoa, Mercedes, Fernández-Lázaro, Diego, Vidriales, Maria-Belen, Galmarini, Carlos M., Avilés, Pablo, Cuevas, Carmen, Pandiella, Atanasio, San-Miguel, Jesús F.
Publicerad 2011

Lurbinectedin inactivates the Ewing sarcoma oncoprotein EWS-FLI1 by redistributing it within the nucleus

av Harlow, Matt L., Maloney, Nichole, Roland, Joseph, Guillen Navarro, Maria Jose, Easton, Matthew K., Kitchen-Goosen, Susan M., Boguslawski, Elissa, Madaj, Zachary B., Johnson, Ben K., Bowman, Megan J., D’Incalci, Maurizio, Winn, Mary E., Turner, Lisa, Hostetter, Galen, Galmarini, Carlos María, Aviles, Pablo, Grohar, Patrick J.
I publikationen Cancer Res (2016)

Evaluation of the Preclinical Efficacy of Lurbinectedin in Malignant Pleural Mesothelioma

av Anobile, Dario P., Bironzo, Paolo, Picca, Francesca, Lingua, Marcello F., Morena, Deborah, Righi, Luisella, Napoli, Francesca, Papotti, Mauro G., Pittaro, Alessandra, Di Nicolantonio, Federica, Gigliotti, Chiara, Bussolino, Federico, Comunanza, Valentina, Guerrera, Francesco, Sandri, Alberto, Leo, Francesco, Libener, Roberta, Aviles, Pablo, Novello, Silvia, Taulli, Riccardo, Scagliotti, Giorgio V., Riganti, Chiara
I publikationen Cancers (Basel) (2021)

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

av Reuschl, Ann-Kathrin, Thorne, Lucy G., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Hiatt, Joseph, Soucheray, Margaret, Turner, Jane, Fabius, Jacqueline M., Nguyen, Gina T., Swaney, Danielle L., Rosales, Romel, White, Kris M., Avilés, Pablo, Kirby, Ilsa T., Melnyk, James E., Shi, Ying, Zhang, Ziyang, Shokat, Kevan M., García-Sastre, Adolfo, Jolly, Clare, Towers, Gregory J., Krogan, Nevan J.
I publikationen bioRxiv (2021)

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

av White, Kris M., Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B., Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M., Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M., Krogan, Nevan J., García-Sastre, Adolfo
I publikationen Science (2021)

Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization

av Varona, José F., Landete, Pedro, Lopez-Martin, Jose A., Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, de Orueta, Lucía Fernández, Torralba, Miguel, Fortún, Jesús, Vates, Roberto, Barberán, José, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemí, Porras, Lourdes, Gijón, Paloma, Monereo, Alfonso, Abad, Daniel, Zúñiga, Sonia, Sola, Isabel, Rodon, Jordi, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, María José, de Rivas, Beatriz, Girón de Velasco, Patricia, Sopesén, Belén, Nieto, Antonio, Gómez, Javier, Avilés, Pablo, Lubomirov, Rubin, White, Kris M., Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G., Jolly, Clare, Towers, Greg J., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Enjuanes, Luis, Fernández-Sousa, Jose M., Krogan, Nevan J., Jimeno, José M., García-Sastre, Adolfo
I publikationen medRxiv (2021)