Developing treatment strategies for rare cancers

Por Atkinson, Jennifer M., Gilbertson, Richard J.
Publicado em 2011

Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model

Por Liu, Qiang, Chen, Longgui, Atkinson, Jennifer M, Claxton, David F, Wang, Hong-Gang
Publicado no Cell Death Dis (2016)

IGF1R Constitutive Activation Expands Luminal Progenitors and Influences Lineage Differentiation During Breast Tumorigenesis

Por Farabaugh, Susan M., Litzenburger, Beate C., Elangovan, Ashuvinee, Pecar, Geoffrey, Walheim, Lauren, Atkinson, Jennifer M., Lee, Adrian V.
Publicado no Dev Biol (2020)

Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma – Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3

Por Atkinson, Jennifer M., Rank, Kenneth B., Zeng, Yi, Capen, Andrew, Yadav, Vipin, Manro, Jason R., Engler, Thomas A., Chedid, Marcio
Publicado no PLoS One (2015)

Time-resolved FRET and NMR analyses reveal selective binding of peptides containing the LC3-interacting region to ATG8 family proteins

Por Atkinson, Jennifer M., Ye, Yansheng, Gebru, Melat T., Liu, Qiang, Zhou, Shouhao, Young, Megan M, Takahashi, Yoshinori, Lin, Qing, Tian, Fang, Wang, Hong-Gang
Publicado no J Biol Chem (2019)

Single-cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells

Por Chen, Fangyuan, Ding, Kai, Priedigkeit, Nolan, Elangovan, Ashuvinee, Levine, Kevin M., Carleton, Neil, Savariau, Laura, Atkinson, Jennifer M., Oesterreich, Steffi, Lee, Adrian V.
Publicado no Cancer Res (2020)

Development of a novel tumor-targeted vascular disrupting agent activated by MT-MMPs

Por Atkinson, Jennifer M, Falconer, Robert A, Edwards, Dylan R, Pennington, Caroline J, Siller, Catherine S, Shnyder, Steven D, Bibby, Michael C, Patterson, Laurence H, Loadman, Paul M, Gill, Jason H
Publicado em 2010

Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection

Por Serfass, Jacob M., Takahashi, Yoshinori, Zhou, Zhixiang, Kawasawa, Yuka Imamura, Liu, Ying, Tsotakos, Nikolaos, Young, Megan M., Tang, Zhenyuan, Yang, Linlin, Atkinson, Jennifer M., Chroneos, Zissis C., Wang, Hong-Gang
Publicado no J Biol Chem (2017)

Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology

Por Blohmer, Martin, Zhu, Li, Atkinson, Jennifer M., Beriwal, Sushil, Rodríguez-López, Joshua L., Rosenzweig, Margaret, Brufsky, Adam M., Tseng, George, Lucas, Peter C., Lee, Adrian V., Oesterreich, Steffi, Jankowitz, Rachel C.
Publicado no Breast Cancer Res (2020)

Loss of E-cadherin enhances IGF1-IGF1R pathway activation and sensitizes breast cancers to anti-IGF1R/InsR inhibitors

Por Nagle, Alison M., Levine, Kevin M., Tasdemir, Nilgun, Scott, Julie A., Burlbaugh, Kara, Kehm, Justin, Katz, Tiffany A., Boone, David N., Jacobsen, Britta M., Atkinson, Jennifer M., Oesterreich, Steffi, Lee, Adrian V.
Publicado no Clin Cancer Res (2018)

An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure

Por Takahashi, Yoshinori, He, Haiyan, Tang, Zhenyuan, Hattori, Tatsuya, Liu, Ying, Young, Megan M., Serfass, Jacob M., Chen, Longgui, Gebru, Melat, Chen, Chong, Wills, Carson A., Atkinson, Jennifer M., Chen, Han, Abraham, Thomas, Wang, Hong-Gang
Publicado no Nat Commun (2018)

Frequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinoma

Por Cao, Lan, Basudan, Ahmed, Sikora, Matthew J, Bahreini, Amir, Tasdemir, Nilgun, Levine, Kevin M, Jankowitz, Rachel C., McAuliffe, Priscilla F, Dabbs, David, Haupt, Sue, Haupt, Ygal, Lucas, Peter C., Lee, Adrian V, Oesterreich, Steffi, Atkinson, Jennifer M
Publicado no Cancer Lett (2019)

Differential Regulation and Targeting of Estrogen Receptor α Turnover in Invasive Lobular Breast Carcinoma

Por Sreekumar, Sreeja, Levine, Kevin M, Sikora, Matthew J, Chen, Jian, Tasdemir, Nilgun, Carter, Dorothy, Dabbs, David J, Meier, Carolin, Basudan, Ahmed, Boone, David, McAuliffe, Priscilla F, Jankowitz, Rachel C, Lee, Adrian V, Atkinson, Jennifer M, Oesterreich, Steffi
Publicado no Endocrinology (2020)

Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia

Por Gebru, Melat T., Atkinson, Jennifer M., Young, Megan M., Zhang, Lijun, Tang, Zhenyuan, Liu, Zhenqiu, Lu, Pinyi, Dower, Christopher M., Chen, Longgui, Annageldiyev, Charyguly, Sharma, Arati, Imamura Kawasawa, Yuka, Zhao, Zhongming, Miller, Barbara A., Claxton, David F., Wang, Hong-Gang
Publicado no Blood (2020)

An integrated in vitro and in vivo high throughput screen identifies treatment leads for ependymoma

Por Atkinson, Jennifer M., Shelat, Anang A., Carcaboso, Angel Montero, Kranenburg, Tanya A., Arnold, Alexander, Boulos, Nidal, Wright, Karen, Johnson, Robert A., Poppleton, Helen, Mohankumar, Kumarasamypet M., Feau, Clementine, Phoenix, Timothy, Gibson, Paul, Zhu, Liqin, Tong, Yiai, Eden, Chris, Ellison, David W., Priebe, Waldemar, Koul, Dimpy, Yung, W. K. Alfred, Gajjar, Amar, Stewart, Clinton F., Guy, R. Kip, Gilbertson, Richard J.
Publicado em 2011

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

Por Johnson, Robert A., Wright, Karen D., Poppleton, Helen, Mohankumar, Kumarasamypet M., Finkelstein, David, Pounds, Stanley B., Rand, Vikki, Leary, Sarah E.S., White, Elsie, Eden, Christopher, Hogg, Twala, Northcott, Paul, Mack, Stephen, Neale, Geoffrey, Wang, Yong-Dong, Coyle, Beth, Atkinson, Jennifer, DeWire, Mariko, Kranenburg, Tanya A., Gillespie, Yancey, Allen, Jeffrey C., Merchant, Thomas, Boop, Fredrick A., Sanford, Robert. A., Gajjar, Amar, Ellison, David W., Taylor, Michael D., Grundy, Richard G., Gilbertson, Richard J.
Publicado em 2010