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An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
The mechanism of phagophore closure remains unclear due to technical limitations in distinguishing unclosed and closed autophagosomal membranes. Here, we report the HaloTag-LC3 autophagosome completion assay that specifically detects phagophores, nascent autophagosomes, and mature autophagic structu...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054611/ https://ncbi.nlm.nih.gov/pubmed/30030437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05254-w |
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