Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis

Autophagosomal membranes are emerging as platforms for various cell survival and death signaling networks beyond autophagy. While autophagy-dependent cell death has been reported in response to a variety of stimuli, the underlying molecular mechanisms remain far from clear. Here, we demonstrate that...

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Vydáno v:Cell Death Differ
Hlavní autoři: Tang, Zhenyuan, Takahashi, Yoshinori, Chen, Chong, Liu, Ying, He, Haiyan, Tsotakos, Nikolaos, Serfass, Jacob M, Gebru, Melat T, Chen, Han, Young, Megan M, Wang, Hong-Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686350/
https://ncbi.nlm.nih.gov/pubmed/28800131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.133
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