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ATG2 regulation of phagophore expansion at mitochondria-associated ER membranes

The mechanism by which ATG2 (ATG2A and ATG2B in mammals) regulates autophagosome biogenesis remains largely unknown. In our recent study, we showed that ATG2A translocates to the mitochondria-associated ER membranes (MAM) to promote phagophore growth during nutrient starvation. Mechanistically, the...

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Publicado en:Autophagy
Autores principales: Tang, Zhenyuan, Takahashi, Yoshinori, Wang, Hong-Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844525/
https://ncbi.nlm.nih.gov/pubmed/31512567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1666594
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