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ATG2 regulation of phagophore expansion at mitochondria-associated ER membranes

The mechanism by which ATG2 (ATG2A and ATG2B in mammals) regulates autophagosome biogenesis remains largely unknown. In our recent study, we showed that ATG2A translocates to the mitochondria-associated ER membranes (MAM) to promote phagophore growth during nutrient starvation. Mechanistically, the...

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Pubblicato in:Autophagy
Autori principali: Tang, Zhenyuan, Takahashi, Yoshinori, Wang, Hong-Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844525/
https://ncbi.nlm.nih.gov/pubmed/31512567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1666594
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