ATG2 regulation of phagophore expansion at mitochondria-associated ER membranes

The mechanism by which ATG2 (ATG2A and ATG2B in mammals) regulates autophagosome biogenesis remains largely unknown. In our recent study, we showed that ATG2A translocates to the mitochondria-associated ER membranes (MAM) to promote phagophore growth during nutrient starvation. Mechanistically, the...

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Bibliographic Details
Published in:Autophagy
Main Authors: Tang, Zhenyuan, Takahashi, Yoshinori, Wang, Hong-Gang
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
Subjects:
Autophagic Punctum
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844525/
https://ncbi.nlm.nih.gov/pubmed/31512567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1666594
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