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The ER-Golgi intermediate compartment feeds the phagophore membrane
A long-standing quest in the autophagy field is to define the membrane origin of the autophagosome. We have established a cell-free assay based on LC3 lipidation that recapitulates multiple regulatory hallmarks of early autophagosome biogenesis. Using a systematic membrane fractionation approach, we...
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Publicado no: | Autophagy |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4389871/ https://ncbi.nlm.nih.gov/pubmed/24220263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26787 |
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