Nalaganje...

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

Autophagy is a catabolic process for bulk degradation of cytosolic materials mediated by double-membraned autophagosomes. The membrane determinant to initiate the formation of autophagosomes remains elusive. Here, we establish a cell-free assay based on LC3 lipidation to define the organelle membran...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ge, Liang, Melville, David, Zhang, Min, Schekman, Randy
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736544/
https://ncbi.nlm.nih.gov/pubmed/23930225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00947
Oznake: Označite
Brez oznak, prvi označite!