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Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

Formation of the autophagosome requires significant membrane input from cellular organelles. However, no direct evidence has been developed to link autophagic factors and the mobilization of membranes to generate the phagophore. Previously, we established a cell-free LC3 lipidation reaction to ident...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ge, Liang, Zhang, Min, Schekman, Randy
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270069/
https://ncbi.nlm.nih.gov/pubmed/25432021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04135
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