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Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

Formation of the autophagosome requires significant membrane input from cellular organelles. However, no direct evidence has been developed to link autophagic factors and the mobilization of membranes to generate the phagophore. Previously, we established a cell-free LC3 lipidation reaction to ident...

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Pubblicato in:eLife
Autori principali: Ge, Liang, Zhang, Min, Schekman, Randy
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270069/
https://ncbi.nlm.nih.gov/pubmed/25432021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04135
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