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The ER-Golgi intermediate compartment feeds the phagophore membrane

A long-standing quest in the autophagy field is to define the membrane origin of the autophagosome. We have established a cell-free assay based on LC3 lipidation that recapitulates multiple regulatory hallmarks of early autophagosome biogenesis. Using a systematic membrane fractionation approach, we...

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Detalles Bibliográficos
Publicado en:Autophagy
Main Authors: Ge, Liang, Schekman, Randy
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389871/
https://ncbi.nlm.nih.gov/pubmed/24220263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26787
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