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ATG2 regulation of phagophore expansion at mitochondria-associated ER membranes

The mechanism by which ATG2 (ATG2A and ATG2B in mammals) regulates autophagosome biogenesis remains largely unknown. In our recent study, we showed that ATG2A translocates to the mitochondria-associated ER membranes (MAM) to promote phagophore growth during nutrient starvation. Mechanistically, the...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Tang, Zhenyuan, Takahashi, Yoshinori, Wang, Hong-Gang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844525/
https://ncbi.nlm.nih.gov/pubmed/31512567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1666594
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