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A requirement for ER-derived COPII vesicles in phagophore initiation

A major unanswered question in the field of autophagy is how the double-membrane phagophore is formed. As this membrane expands, it engulfs proteins and organelles that are destined for degradation and then seals to form an autophagosome. A growing consensus in the field is that a subdomain of the E...

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Main Authors: Wang, Juan, Tan, Dongyan, Cai, Yiying, Reinisch, Karin M, Walz, Thomas, Ferro-Novick, Susan
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091162/
https://ncbi.nlm.nih.gov/pubmed/24561915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28103
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