Emerging strategies to deplete the HIV reservoir

Por Archin, Nancie M., Margolis, David M.
Publicado em 2014

Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents

Por Margolis, David M., Archin, Nancie M.
Publicado no J Infect Dis (2017)

Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid

Por Archin, Nancie M., Espeseth, Amy, Parker, Daniel, Cheema, Manzoor, Hazuda, Daria, Margolis, David M.
Publicado em 2009

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

Por Archin, Nancie M., Sung, Julia Marsh, Garrido, Carolina, Soriano-Sarabia, Natalia, Margolis, David M.
Publicado no Nat Rev Microbiol (2014)

A Limited Group of Class I Histone Deacetylases Acts To Repress Human Immunodeficiency Virus Type 1 Expression

Por Keedy, Kara S., Archin, Nancie M., Gates, Adam T., Espeseth, Amy, Hazuda, Daria J., Margolis, David M.
Publicado em 2009

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

Por Archin, Nancie M., Keedy, Kara S., Espeseth, Amy, Dang, Herbert, Hazuda, Daria J., Margolis, David M.
Publicado em 2009

Latent HIV-1 Infection of Resting CD4(+) T Cells in the Humanized Rag2(−/−) γ(c)(−/−) Mouse

Por Choudhary, Shailesh K., Archin, Nancie M., Cheema, Manzoor, Dahl, Noelle P., Garcia, J. Victor, Margolis, David M.
Publicado em 2012

H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4(+) T Cells

Por Tripathy, Manoj K., McManamy, Mary E. M., Burch, Brandon D., Archin, Nancie M., Margolis, David M.
Publicado no J Virol (2015)

Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2

Por Friedman, Julia, Cho, Won-Kyung, Chu, Chung K., Keedy, Kara S., Archin, Nancie M., Margolis, David M., Karn, Jonathan
Publicado em 2011

Quantification of the Latent HIV-1 Reservoir Using Ultra Deep Sequencing and Primer ID In A Viral Outgrowth Assay

Por Lee, Sook-Kyung, Zhou, Shuntai, Baldoni, Pedro L., Spielvogel, Ean, Archin, Nancie M., Hudgens, Michael G., Margolis, David M., Swanstrom, Ronald
Publicado no J Acquir Immune Defic Syndr (2017)

Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection

Por Archin, Nancie M., Cheema, Manzoor, Parker, Daniel, Wiegand, Ann, Bosch, Ronald J., Coffin, John M., Eron, Joseph, Cohen, Myron, Margolis, David M.
Publicado em 2010

Quantitation of Replication-Competent HIV-1 in Populations of Resting CD4(+) T Cells

Por Soriano-Sarabia, Natalia, Bateson, Rosalie E., Dahl, Noelle P., Crooks, Amanda M., Kuruc, JoAnn D., Margolis, David M., Archin, Nancie M.
Publicado no J Virol (2014)

Reactivation of latent HIV-1 in central memory CD4(+) T cells through TLR-1/2 stimulation

Por Novis, Camille L, Archin, Nancie M, Buzon, Maria J, Verdin, Eric, Round, June L, Lichterfeld, Mathias, Margolis, David M, Planelles, Vicente, Bosque, Alberto
Publicado em 2013

Peripheral Vγ9Vδ2 T Cells Are a Novel Reservoir of Latent HIV Infection

Por Soriano-Sarabia, Natalia, Archin, Nancie M., Bateson, Rosalie, Dahl, Noelle P., Crooks, Amanda M., Kuruc, JoAnn D., Garrido, Carolina, Margolis, David M.
Publicado no PLoS Pathog (2015)

Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection

Por Barton, Kirston M., Archin, Nancie M., Keedy, Kara S., Espeseth, Amy S., Zhang, Yan-ling, Gale, Jennifer, Wagner, Florence F., Holson, Edward B., Margolis, David M.
Publicado em 2014

Clonal Sequences Recovered from Plasma from Patients with Residual HIV-1 Viremia and on Intensified Antiretroviral Therapy Are Identical to Replicating Viral RNAs Recovered from Ci...

Por Anderson, Jeffrey A., Archin, Nancie M., Ince, William, Parker, Daniel, Wiegand, Ann, Coffin, John M., Kuruc, JoAnn, Eron, Joseph, Swanstrom, Ronald, Margolis, David M.
Publicado em 2011

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

Por Sung, Julia A., Sholtis, Katherine, Kirchherr, Jennifer, Kuruc, Joann D., Gay, Cynthia L., Nordstrom, Jeffrey L., Bollard, Catherine M., Archin, Nancie M., Margolis, David M.
Publicado no EBioMedicine (2017)

In vivo analysis of the effect of panobinostat on cell-associated HIV RNA and DNA levels and latent HIV infection

Por Tsai, Perry, Wu, Guoxin, Baker, Caroline E., Thayer, William O., Spagnuolo, Rae Ann, Sanchez, Rosa, Barrett, Stephanie, Howell, Bonnie, Margolis, David, Hazuda, Daria J., Archin, Nancie M., Garcia, J. Victor
Publicado no Retrovirology (2016)

HLA-B*57 Elite Suppressor and Chronic Progressor HIV-1 Isolates Replicate Vigorously and Cause CD4(+) T Cell Depletion in Humanized BLT Mice

Por Salgado, Maria, Swanson, Michael D., Pohlmeyer, Christopher W., Buckheit, Robert W., Wu, Jin, Archin, Nancie M., Williams, Thomas M., Margolis, David M., Siliciano, Robert F., Garcia, J. Victor, Blankson, Joel N.
Publicado em 2014

Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies

Por Crooks, Amanda M., Bateson, Rosalie, Cope, Anna B., Dahl, Noelle P., Griggs, Morgan K., Kuruc, JoAnn D., Gay, Cynthia L., Eron, Joseph J., Margolis, David M., Bosch, Ronald J., Archin, Nancie M.
Publicado no J Infect Dis (2015)