Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

Latently human immunodeficiency virus (HIV)-infected cells are transcriptionally quiescent and invisible to clearance by the immune system. To demonstrate that the latency reversing agent vorinostat (VOR) induces a window of vulnerability in the latent HIV reservoir, defined as the triggering of vir...

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Publicado en:EBioMedicine
Autores principales: Sung, Julia A., Sholtis, Katherine, Kirchherr, Jennifer, Kuruc, Joann D., Gay, Cynthia L., Nordstrom, Jeffrey L., Bollard, Catherine M., Archin, Nancie M., Margolis, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605299/
https://ncbi.nlm.nih.gov/pubmed/28803740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.07.019
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