Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Quantifying the inducible HIV reservoir provides an estimate of the frequency of quiescent HIV-infected cells in humans as well as in animal models, and can help ascertain the efficacy of latency reversing agents (LRAs). The quantitative viral outgrowth assay (QVOA) is used to measure inducible, rep...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Stuelke, Erin L., James, Katherine S., Kirchherr, Jennifer L., Allard, Brigitte, Baker, Caroline, Kuruc, Joann D., Gay, Cindy L., Margolis, David M., Archin, Nancie M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423995/
https://ncbi.nlm.nih.gov/pubmed/32849659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01971
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