Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Quantifying the inducible HIV reservoir provides an estimate of the frequency of quiescent HIV-infected cells in humans as well as in animal models, and can help ascertain the efficacy of latency reversing agents (LRAs). The quantitative viral outgrowth assay (QVOA) is used to measure inducible, rep...

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發表在:Front Immunol
Main Authors: Stuelke, Erin L., James, Katherine S., Kirchherr, Jennifer L., Allard, Brigitte, Baker, Caroline, Kuruc, Joann D., Gay, Cindy L., Margolis, David M., Archin, Nancie M.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423995/
https://ncbi.nlm.nih.gov/pubmed/32849659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01971
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