Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Quantifying the inducible HIV reservoir provides an estimate of the frequency of quiescent HIV-infected cells in humans as well as in animal models, and can help ascertain the efficacy of latency reversing agents (LRAs). The quantitative viral outgrowth assay (QVOA) is used to measure inducible, rep...

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Vydáno v:Front Immunol
Hlavní autoři: Stuelke, Erin L., James, Katherine S., Kirchherr, Jennifer L., Allard, Brigitte, Baker, Caroline, Kuruc, Joann D., Gay, Cindy L., Margolis, David M., Archin, Nancie M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423995/
https://ncbi.nlm.nih.gov/pubmed/32849659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01971
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