Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Quantifying the inducible HIV reservoir provides an estimate of the frequency of quiescent HIV-infected cells in humans as well as in animal models, and can help ascertain the efficacy of latency reversing agents (LRAs). The quantitative viral outgrowth assay (QVOA) is used to measure inducible, rep...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Stuelke, Erin L., James, Katherine S., Kirchherr, Jennifer L., Allard, Brigitte, Baker, Caroline, Kuruc, Joann D., Gay, Cindy L., Margolis, David M., Archin, Nancie M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423995/
https://ncbi.nlm.nih.gov/pubmed/32849659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01971
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