Cancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in Cancer

Por Altman, Brian J.
Publicado no Front Cell Dev Biol (2016)

Autophagy: Not good OR bad, but good AND bad

Por Altman, Brian J., Rathmell, Jeffrey C.
Publicado em 2009

Metabolic Stress in Autophagy and Cell Death Pathways

Por Altman, Brian J., Rathmell, Jeffrey C.
Publicado em 2012

From Krebs to Clinic: Glutamine Metabolism to Cancer Therapy

Por Altman, Brian J., Stine, Zachary E., Dang, Chi V.
Publicado no Nat Rev Cancer (2016)

Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα

Por Altman, Brian J., Hsieh, Annie L., Gouw, Arvin M., Dang, Chi V.
Publicado no Nat Commun (2017)

Telomerase can act as a template- and RNA-independent terminal transferase

Por Lue, Neal F., Bosoy, Dimitry, Moriarty, Tara J., Autexier, Chantal, Altman, Brian, Leng, Siyang
Publicado em 2005

MYC, Metabolism, and Cancer

Por Stine, Zachary E., Walton, Zandra E., Altman, Brian J., Hsieh, Annie L., Dang, Chi V.
Publicado no Cancer Discov (2015)

MYC and metabolism on the path to cancer

Por Hsieh, Annie L., Walton, Zandra E., Altman, Brian J., Stine, Zachary E., Dang, Chi V.
Publicado no Semin Cell Dev Biol (2015)

An Essential Role for the Glut1 PDZ-Binding Motif in Growth Factor Regulation of Glut1 Degradation and Trafficking

Por Wieman, Heather L., Horn, Sarah R., Jacobs, Sarah R., Altman, Brian J., Kornbluth, Sally, Rathmell, Jeffrey C.
Publicado em 2009

ER Stress Modulates Cellular Metabolism

Por Wang, Xiaoli, Eno, Colins O., Altman, Brian J., Zhu, Yanglong, Zhao, Guoping, Olberding, Kristen E., Rathmell, Jeffrey C., Li, Chi
Publicado em 2011

Autophagy Provides Nutrients but Can Lead to Chop-dependent Induction of Bim to Sensitize Growth Factor–deprived Cells to Apoptosis

Por Altman, Brian J., Wofford, Jessica A., Zhao, Yuxing, Coloff, Jonathan L., Ferguson, Emily C., Wieman, Heather L., Day, Amanda E., Ilkayeva, Olga, Rathmell, Jeffrey C.
Publicado em 2009

Autophagy is Essential to Suppress Cell Stress and to Allow BCR-Abl-Mediated Leukemogenesis

Por Altman, Brian J., Jacobs, Sarah R., Mason, Emily F., Michalek, Ryan D., MacIntyre, Andrew N., Coloff, Jonathon L., Ilkayeva, Olga, Jia, Wei, He, You-Wen, Rathmell, Jeffrey C.
Publicado em 2010

Glycogen Synthase Kinase 3α and 3β Mediate a Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1

Por Zhao, Yuxing, Altman, Brian J., Coloff, Jonathan L., Herman, Catherine E., Jacobs, Sarah R., Wieman, Heather L., Wofford, Jessica A., Dimascio, Leah N., Ilkayeva, Olga, Kelekar, Ameeta, Reya, Tannishtha, Rathmell, Jeffrey C.
Publicado em 2007

TM-06 MYC AND MYCN DISRUPTION OF THE MOLECULAR CLOCK IN CANCER CELLS

Por Hsieh, Annie, Altman, Brian, Stine, Zach, Gouw, Arvin, Venkataraman, Anand, Li, Bo, Goraksha-Hicks, Pankuri, Diskin, Sharon, Bellovin, David, Celeste Simon, M., Rathmell, Jeffrey, Lazar, Mitch, Maris, John, Felsher, Dean, Hogenesch, John, Dang, Chi
Publicado no Neuro Oncol (2014)

Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells

Por Coloff, Jonathan L., Mason, Emily F., Altman, Brian J., Gerriets, Valerie A., Liu, Tingyu, Nichols, Amanda N., Zhao, Yuxing, Wofford, Jessica A., Jacobs, Sarah R., Ilkayeva, Olga, Garrison, Sean P., Zambetti, Gerard P., Rathmell, Jeffrey C.
Publicado em 2011

A PERK-miR211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival

Por Bu, Yiwen, Yoshida, Akihiro, Chitnis, Nilesh, Altman, Brian J., Tameire, Feven, Oran, Amanda, Gennaro, Victoria, Armeson, Kent E., McMahon, Steven, Wertheim, Gerald B., Van Dang, Chi, Ruggero, Davide, Koumenis, Constantinos, Fuchs, Serge Y., Diehl, J. Alan
Publicado no Nat Cell Biol (2017)

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells

Por Altman, Brian J., Hsieh, Annie L., Sengupta, Arjun, Krishnanaiah, Saikumari Y., Stine, Zachary E., Walton, Zandra E., Gouw, Arvin M., Venkataraman, Anand, Li, Bo, Goraksha-Hicks, Pankuri, Diskin, Sharon J., Bellovin, David I., Simon, M. Celeste, Rathmell, Jeffrey C., Lazar, Mitchell A., Maris, John M., Felsher, Dean W., Hogenesch, John B., Weljie, Aalim M., Dang, Chi V.
Publicado no Cell Metab (2015)

Clock regulation of metabolites reveals coupling between transcription and metabolism

Por Krishnaiah, Saikumari Y., Wu, Gang, Altman, Brian J., Growe, Jacqueline, Rhoades, Seth D., Coldren, Faith, Venkataraman, Anand, Olarerin-George, Anthony O., Francey, Lauren J., Mukherjee, Sarmistha, Girish, Saiveda, Selby, Christopher P., Cal, Sibel, Ubeydullah, ER, Sianati, Bahareh, Sengupta, Arjun, Anafi, Ron C., Kavakli, I. Halil, Sancar, Aziz, Baur, Joseph A., Dang, Chi V., Hogenesch, John B., Weljie, Aalim M.
Publicado no Cell Metab (2017)

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

Por Xiang, Yan, Stine, Zachary E., Xia, Jinsong, Lu, Yunqi, O’Connor, Roddy S., Altman, Brian J., Hsieh, Annie L., Gouw, Arvin M., Thomas, Ajit G., Gao, Ping, Sun, Linchong, Song, Libing, Yan, Benedict, Slusher, Barbara S., Zhuo, Jingli, Ooi, London L., Lee, Caroline G.L., Mancuso, Anthony, McCallion, Andrew S., Le, Anne, Milone, Michael C., Rayport, Stephen, Felsher, Dean W., Dang, Chi V.
Publicado no J Clin Invest (2015)