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Telomerase can act as a template- and RNA-independent terminal transferase
Telomerase is a special reverse transcriptase that extends one strand of the telomere repeat by using a template embedded in an RNA subunit. Like other polymerases, telomerase is believed to use a pair of divalent metal ions (coordinated by a triad of aspartic acid residues) for catalyzing nucleotid...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174988/ https://ncbi.nlm.nih.gov/pubmed/15994230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502252102 |
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