Functional Organization of Repeat Addition Processivity and DNA Synthesis Determinants in the Human Telomerase Multimer

Human telomerase is a multimer containing two human telomerase RNAs (hTRs) and most likely two human telomerase reverse transcriptases (hTERTs). Telomerase synthesizes multiple telomeric repeats using a unique repeat addition form of processivity. We investigated hTR and hTERT sequences that were es...

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Detalhes bibliográficos
Main Authors: Moriarty, Tara J., Marie-Egyptienne, Delphine T., Autexier, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387747/
https://ncbi.nlm.nih.gov/pubmed/15082768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3720-3733.2004
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