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Functional Organization of Repeat Addition Processivity and DNA Synthesis Determinants in the Human Telomerase Multimer

Human telomerase is a multimer containing two human telomerase RNAs (hTRs) and most likely two human telomerase reverse transcriptases (hTERTs). Telomerase synthesizes multiple telomeric repeats using a unique repeat addition form of processivity. We investigated hTR and hTERT sequences that were es...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Moriarty, Tara J., Marie-Egyptienne, Delphine T., Autexier, Chantal
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082768/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.3720-3733.2004
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