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The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity

The catalytic subunit of telomerase (TERT) contains conserved reverse transcriptase-like motifs but N- and C-terminal regions unique to telomerases. Despite weak sequence conservation, the C terminus of TERTs from various organisms has been implicated in telomerase-specific functions, including telo...

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Detalhes bibliográficos
Main Authors: Huard, Sylvain, Moriarty, Tara J., Autexier, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165952/
https://ncbi.nlm.nih.gov/pubmed/12853623
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