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The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity

The catalytic subunit of telomerase (TERT) contains conserved reverse transcriptase-like motifs but N- and C-terminal regions unique to telomerases. Despite weak sequence conservation, the C terminus of TERTs from various organisms has been implicated in telomerase-specific functions, including telo...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Huard, Sylvain, Moriarty, Tara J., Autexier, Chantal
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853623/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg437
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