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N-Terminal Domains of the Human Telomerase Catalytic Subunit Required for Enzyme Activity in Vivo

Most tumor cells depend upon activation of the ribonucleoprotein enzyme telomerase for telomere maintenance and continual proliferation. The catalytic activity of this enzyme can be reconstituted in vitro with the RNA (hTR) and catalytic (hTERT) subunits. However, catalytic activity alone is insuffi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Armbruster, Blaine N., Banik, Soma S. R., Guo, Chuanhai, Smith, Allyson C., Counter, Christopher M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC99947/
https://ncbi.nlm.nih.gov/pubmed/11604512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7775-7786.2001
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