N-Terminal Domains of the Human Telomerase Catalytic Subunit Required for Enzyme Activity in Vivo

Most tumor cells depend upon activation of the ribonucleoprotein enzyme telomerase for telomere maintenance and continual proliferation. The catalytic activity of this enzyme can be reconstituted in vitro with the RNA (hTR) and catalytic (hTERT) subunits. However, catalytic activity alone is insuffi...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Armbruster, Blaine N., Banik, Soma S. R., Guo, Chuanhai, Smith, Allyson C., Counter, Christopher M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11604512/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.22.7775-7786.2001
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