N-Terminal Domains of the Human Telomerase Catalytic Subunit Required for Enzyme Activity in Vivo
Most tumor cells depend upon activation of the ribonucleoprotein enzyme telomerase for telomere maintenance and continual proliferation. The catalytic activity of this enzyme can be reconstituted in vitro with the RNA (hTR) and catalytic (hTERT) subunits. However, catalytic activity alone is insuffi...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11604512/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.22.7775-7786.2001 |
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