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Regulation of 5′ template usage and incorporation of noncognate nucleotides by human telomerase

Telomerase accurately synthesizes telomeric DNA by reverse transcription of a tightly defined template region in the telomerase RNA (TR). Reverse transcription past the 5′ boundary of the template can cause the incorporation of noncognate nucleotides into telomeric DNA, which can result in disruptio...

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Detalhes bibliográficos
Main Authors: MORIARTY, TARA J., MARIE-EGYPTIENNE, DELPHINE T., AUTEXIER, CHANTAL
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370828/
https://ncbi.nlm.nih.gov/pubmed/16120835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2910105
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