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Regulation of 5′ template usage and incorporation of noncognate nucleotides by human telomerase

Telomerase accurately synthesizes telomeric DNA by reverse transcription of a tightly defined template region in the telomerase RNA (TR). Reverse transcription past the 5′ boundary of the template can cause the incorporation of noncognate nucleotides into telomeric DNA, which can result in disruptio...

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Autori principali: MORIARTY, TARA J., MARIE-EGYPTIENNE, DELPHINE T., AUTEXIER, CHANTAL
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2005 by RNA Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370828/
https://ncbi.nlm.nih.gov/pubmed/16120835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2910105
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