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Regulation of 5′ template usage and incorporation of noncognate nucleotides by human telomerase
Telomerase accurately synthesizes telomeric DNA by reverse transcription of a tightly defined template region in the telomerase RNA (TR). Reverse transcription past the 5′ boundary of the template can cause the incorporation of noncognate nucleotides into telomeric DNA, which can result in disruptio...
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright 2005 by RNA Society
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370828/ https://ncbi.nlm.nih.gov/pubmed/16120835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2910105 |
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