TM-06 MYC AND MYCN DISRUPTION OF THE MOLECULAR CLOCK IN CANCER CELLS

Cancer cells are known to have a metabolic advantage, but it is not known whether the circadian clock, which couples metabolic and cell cycles, restrains cancer cell metabolism and growth. We report that the deregulated expression of the MYC or MYCN oncogene disrupts the molecular clock by inducing...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hsieh, Annie, Altman, Brian, Stine, Zach, Gouw, Arvin, Venkataraman, Anand, Li, Bo, Goraksha-Hicks, Pankuri, Diskin, Sharon, Bellovin, David, Celeste Simon, M., Rathmell, Jeffrey, Lazar, Mitch, Maris, John, Felsher, Dean, Hogenesch, John, Dang, Chi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218630/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.6
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