An Essential Role for the Glut1 PDZ-Binding Motif in Growth Factor Regulation of Glut1 Degradation and Trafficking

Cell surface localization of the glucose transporter, Glut1, is a cytokine-controlled process essential to support the metabolism and survival of hematopoietic cells. Molecular mechanisms that regulate Glut1 trafficking, however, are not certain. Here we show a C-terminal PDZ-binding motif in Glut1...

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Main Authors: Wieman, Heather L., Horn, Sarah R., Jacobs, Sarah R., Altman, Brian J., Kornbluth, Sally, Rathmell, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637307/
https://ncbi.nlm.nih.gov/pubmed/19016655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081422
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