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The PDZ-binding motif of the β(2)-adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes

β(1)- and β(2)-adrenergic receptors (AR) regulate cardiac myocyte function through distinct signaling pathways. In addition to regulating cardiac rate and contractility, β(1)AR and β(2)AR may play different roles in the pathogenesis of heart failure. Studies on neonatal cardiac myocytes from β(1)AR...

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Detalhes bibliográficos
Main Authors: Xiang, Yang, Kobilka, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196879/
https://ncbi.nlm.nih.gov/pubmed/12954981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1831718100
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