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The PDZ-binding motif of the β(2)-adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes

β(1)- and β(2)-adrenergic receptors (AR) regulate cardiac myocyte function through distinct signaling pathways. In addition to regulating cardiac rate and contractility, β(1)AR and β(2)AR may play different roles in the pathogenesis of heart failure. Studies on neonatal cardiac myocytes from β(1)AR...

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Bibliografiske detaljer
Main Authors: Xiang, Yang, Kobilka, Brian
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196879/
https://ncbi.nlm.nih.gov/pubmed/12954981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1831718100
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