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WNK1 kinase is essential for insulin‐stimulated GLUT4 trafficking in skeletal muscle

With‐no‐lysine 1 (WNK1) kinase is a substrate of the insulin receptor/Akt pathway. Impaired insulin signaling in skeletal muscle disturbs glucose transporter 4 (GLUT4) translocation associated with the onset of type 2 diabetes (T2D). WNK1 is highly expressed in skeletal muscle. However, it is curren...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS Open Bio
Prif Awduron: Kim, Ji‐Hee, Kim, Hanul, Hwang, Kyu‐Hee, Chang, Jae Seung, Park, Kyu‐Sang, Cha, Seung‐Kuy, Kong, In Deok
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212645/
https://ncbi.nlm.nih.gov/pubmed/30410865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12528
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