Biological Role of Anti-aging Protein Klotho

Klotho-deficient mice have accelerated aging phenotypes, whereas overexpression of Klotho in mice extends lifespan. Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circu...

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Foilsithe in:J Lifestyle Med
Main Authors: Kim, Ji-Hee, Hwang, Kyu-Hee, Park, Kyu-Sang, Kong, In Deok, Cha, Seung-Kuy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Yonsei University Wonju College of Medicine 2015
Ábhair:
Review Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608225/
https://ncbi.nlm.nih.gov/pubmed/26528423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15280/jlm.2015.5.1.1
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