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Biological Role of Anti-aging Protein Klotho
Klotho-deficient mice have accelerated aging phenotypes, whereas overexpression of Klotho in mice extends lifespan. Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circu...
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| Publicado no: | J Lifestyle Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Yonsei University Wonju College of Medicine
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608225/ https://ncbi.nlm.nih.gov/pubmed/26528423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15280/jlm.2015.5.1.1 |
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