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WNK4 Kinase Stimulates Caveola-mediated Endocytosis of TRPV5 Amplifying the Dynamic Range of Regulation of the Channel by Protein Kinase C

WNK4 (with-no-lysine (K) kinase-4) is present in the distal nephron of the kidney and plays an important role in the regulation of renal ion transport. The epithelial Ca(2+) channel TRPV5 (transient receptor potential vanilloid 5) is the gatekeeper of transcellular Ca(2+) reabsorption in the distal...

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Detalhes bibliográficos
Main Authors: Cha, Seung-Kuy, Huang, Chou-Long
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825456/
https://ncbi.nlm.nih.gov/pubmed/20061383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056044
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