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Flow-Induced Activation of TRPV5 and TRPV6 Channel Stimulates Ca(2+)-Activated K(+) Channel Causing Membrane Hyperpolarization
TRPV5 and TRPV6 channels are expressed in distal renal tubules and play important roles in the transcellular Ca(2+) reabsorption in kidney. They are regulated by multiple intracellular factors including protein kinase A and C, membrane phospholipid PIP(2), protons, and divalent ions Ca(2+) and Mg(2+...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932323/ https://ncbi.nlm.nih.gov/pubmed/24001793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.08.017 |
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