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PIP(2) Activates TRPV5 and Releases Its Inhibition by Intracellular Mg(2+)

The transient receptor potential type V5 channel (TRPV5) is a Ca(2+)-selective TRP channel important for epithelial Ca(2+) transport. Intracellular Mg(2+) causes a fast voltage-dependent block of the TRPV5 channel by binding to the selectivity filter. Here, we report that intracellular Mg(2+) bindin...

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Autors principals: Lee, Jason, Cha, Seung-Kuy, Sun, Tie-Jun, Huang, Chou-Long
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266600/
https://ncbi.nlm.nih.gov/pubmed/16230466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509314
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