Loading...

IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

Lymphocyte homeostasis requires coordination of metabolic processes with cellular energetic and biosynthetic demands but mechanisms that regulate T-cell metabolism are uncertain. We show that interleukin-7 (IL-7) is a key regulator of glucose uptake in T lymphocytes. To determine how IL-7 affects gl...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wofford, Jessica A., Wieman, Heather L., Jacobs, Sarah R., Zhao, Yuxing, Rathmell, Jeffrey C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234050/
https://ncbi.nlm.nih.gov/pubmed/18042802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-096297
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!