Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells

The PI3K/Akt pathway is activated in stimulated cells and in many cancers to promote glucose metabolism and prevent cell death. Although inhibition of Akt-mediated cell survival may provide a means to eliminate cancer cells, this survival pathway remains incompletely understood. In particular, unlik...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Coloff, Jonathan L., Mason, Emily F., Altman, Brian J., Gerriets, Valerie A., Liu, Tingyu, Nichols, Amanda N., Zhao, Yuxing, Wofford, Jessica A., Jacobs, Sarah R., Ilkayeva, Olga, Garrison, Sean P., Zambetti, Gerard P., Rathmell, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037705/
https://ncbi.nlm.nih.gov/pubmed/21159778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.179101
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados