Glycogen Synthase Kinase 3α and 3β Mediate a Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1

Glucose uptake and utilization are growth factor-stimulated processes that are frequently upregulated in cancer cells and that correlate with enhanced cell survival. The mechanism of metabolic protection from apoptosis, however, has been unclear. Here we identify a novel signaling pathway initiated...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Yuxing, Altman, Brian J., Coloff, Jonathan L., Herman, Catherine E., Jacobs, Sarah R., Wieman, Heather L., Wofford, Jessica A., Dimascio, Leah N., Ilkayeva, Olga, Kelekar, Ameeta, Reya, Tannishtha, Rathmell, Jeffrey C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900055/
https://ncbi.nlm.nih.gov/pubmed/17371841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00153-07
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