Clock regulation of metabolites reveals coupling between transcription and metabolism

The intricate connection between the circadian clock and metabolism remains poorly understood. We used high temporal resolution metabolite profiling to explore clock regulation of mouse liver and cell autonomous metabolism. In liver, ~50% of metabolites were circadian, with enrichment of nucleotide,...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Krishnaiah, Saikumari Y., Wu, Gang, Altman, Brian J., Growe, Jacqueline, Rhoades, Seth D., Coldren, Faith, Venkataraman, Anand, Olarerin-George, Anthony O., Francey, Lauren J., Mukherjee, Sarmistha, Girish, Saiveda, Selby, Christopher P., Cal, Sibel, Ubeydullah, ER, Sianati, Bahareh, Sengupta, Arjun, Anafi, Ron C., Kavakli, I. Halil, Sancar, Aziz, Baur, Joseph A., Dang, Chi V., Hogenesch, John B., Weljie, Aalim M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479132/
https://ncbi.nlm.nih.gov/pubmed/28380384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.019
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