Clock regulation of metabolites reveals coupling between transcription and metabolism

The intricate connection between the circadian clock and metabolism remains poorly understood. We used high temporal resolution metabolite profiling to explore clock regulation of mouse liver and cell autonomous metabolism. In liver, ~50% of metabolites were circadian, with enrichment of nucleotide,...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Krishnaiah, Saikumari Y., Wu, Gang, Altman, Brian J., Growe, Jacqueline, Rhoades, Seth D., Coldren, Faith, Venkataraman, Anand, Olarerin-George, Anthony O., Francey, Lauren J., Mukherjee, Sarmistha, Girish, Saiveda, Selby, Christopher P., Cal, Sibel, Ubeydullah, ER, Sianati, Bahareh, Sengupta, Arjun, Anafi, Ron C., Kavakli, I. Halil, Sancar, Aziz, Baur, Joseph A., Dang, Chi V., Hogenesch, John B., Weljie, Aalim M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479132/
https://ncbi.nlm.nih.gov/pubmed/28380384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.019
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