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Comprehensive Optimization of LC-MS Metabolomics Methods Using Design of Experiments (COLMeD)
INTRODUCTION: Both reverse-phase and HILIC chemistries are deployed for liquid-chromatography mass spectrometry (LC-MS) metabolomics analyses, however HILIC methods lag behind reverse-phase methods in reproducibility and versatility. Comprehensive metabolomics analysis is additionally complicated by...
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| Veröffentlicht in: | Metabolomics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5364801/ https://ncbi.nlm.nih.gov/pubmed/28348510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1132-4 |
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