Clock regulation of metabolites reveals coupling between transcription and metabolism

The intricate connection between the circadian clock and metabolism remains poorly understood. We used high temporal resolution metabolite profiling to explore clock regulation of mouse liver and cell autonomous metabolism. In liver, ~50% of metabolites were circadian, with enrichment of nucleotide,...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Krishnaiah, Saikumari Y., Wu, Gang, Altman, Brian J., Growe, Jacqueline, Rhoades, Seth D., Coldren, Faith, Venkataraman, Anand, Olarerin-George, Anthony O., Francey, Lauren J., Mukherjee, Sarmistha, Girish, Saiveda, Selby, Christopher P., Cal, Sibel, Ubeydullah, ER, Sianati, Bahareh, Sengupta, Arjun, Anafi, Ron C., Kavakli, I. Halil, Sancar, Aziz, Baur, Joseph A., Dang, Chi V., Hogenesch, John B., Weljie, Aalim M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479132/
https://ncbi.nlm.nih.gov/pubmed/28380384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.019
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