The Mitochondrion Is a Site of Trypanocidal Action of the Aromatic Diamidine DB75 in Bloodstream Forms of Trypanosoma brucei

Por Lanteri, Charlotte A., Tidwell, Richard R., Meshnick, Steven R.
Publicado em 2008

Interactions of DB75, a Novel Antimalarial Agent, with Other Antimalarial Drugs In Vitro

Por Purfield, Anne E., Tidwell, Richard R., Meshnick, Steven R.
Publicado em 2008

The diamidine DB75 targets the nucleus of Plasmodium falciparum

Por Purfield, Anne E, Tidwell, Richard R, Meshnick, Steven R
Publicado em 2009

Pentamidine Congeners 1: Synthesis of Cis- and Trans-Butamidine Analogues As Anti-Pneumocystis carinii Pneumonia Agents

Por Donkor, Isaac O., Jones, Susan K., Tidwell, Richard R.
Publicado em 1993

Novel Diamidines with Activity against Babesia divergens In Vitro and Babesia microti In Vivo

Por Nehrbass-Stuedli, Angela, Boykin, David, Tidwell, Richard R., Brun, Reto
Publicado em 2011

DB75, a Novel Trypanocidal Agent, Disrupts Mitochondrial Function in Saccharomyces cerevisiae

Por Lanteri, Charlotte A., Trumpower, Bernard L., Tidwell, Richard R., Meshnick, Steven R.
Publicado em 2004

In Vivo Investigations of Selected Diamidine Compounds against Trypanosoma evansi Using a Mouse Model

Por Gillingwater, Kirsten, Kumar, Arvind, Anbazhagan, Mariappan, Boykin, David W., Tidwell, Richard R., Brun, Reto
Publicado em 2009

In Vitro, Ex Vivo, and In Vivo Activities of Diamidines against Trypanosoma congolense and Trypanosoma vivax

Por Gillingwater, Kirsten, Kunz, Christina, Braghiroli, Christiane, Boykin, David W., Tidwell, Richard R., Brun, Reto
Publicado no Antimicrob Agents Chemother (2017)

Designed compounds for recognition of ten base pairs of DNA with two AT binding sites

Por Liu, Yang, Chai, Yun, Kumar, Arvind, Tidwell, Richard R., Boykin, David W., Wilson, W. David
Publicado em 2012

Immunoassays for pentamidine and related compounds: Development of a facile inhibitory ELISA suitable for clinical use

Por Reisner, Howard M., Gray, Danny R., Jones, Susan K., Rose, Beate G., Tidwell, Richard R.
Publicado no J Clin Lab Anal (2000)

New Treatment Option for Second-Stage African Sleeping Sickness: In Vitro and In Vivo Efficacy of Aza Analogs of DB289

Por Wenzler, Tanja, Boykin, David W., Ismail, Mohamed A., Hall, James Edwin, Tidwell, Richard R., Brun, Reto
Publicado em 2009

Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense

Por Patrick, Donald A., Wenzler, Tanja, Yang, Sihyung, Weiser, Patrick T., Wang, Michael Zhuo, Brun, Reto, Tidwell, Richard R.
Publicado no Bioorg Med Chem (2016)

Application of monoclonal antibodies to measure metabolism of an anti‐trypanosomal compound in vitro and in vivo

Por Goldsmith, Rachel Beaulieu, Gray, Danny R., Yan, Zhixia, Generaux, Claudia N., Tidwell, Richard R., Reisner, Howard M.
Publicado no J Clin Lab Anal (2010)

Erratum: Application of monoclonal antibodies to measure metabolism of an anti‐trypanosomal compound in vitro and in vivo

Por Goldsmith, Rachel Beaulieu, Gray, Danny R., Yan, Zhixia, Generaux, Claudia N., Tidwell, Richard R., Reisner, Howard M.
Publicado no J Clin Lab Anal (2011)

Synthesis and Antiprotozoal Activity of Cationic 1,4-Diphenyl-1H-1,2,3-Triazoles

Por Bakunov, Stanislav A., Bakunova, Svetlana M., Wenzler, Tanja, Ghebru, Maedot, Werbovetz, Karl A., Brun, Reto, Tidwell, Richard R.
Publicado em 2010

Minor Groove Binding Compounds That Jump a GC Base Pair and Bind to Adjacent AT Base Pair Sites()

Por Rahimian, Maryam, Kumar, Arvind, Say, Martial, Bakunov, Stanislav A., Boykin, David W., Tidwell, Richard R., Wilson, W. David
Publicado em 2009

Antileishmanial Activities of Several Classes of Aromatic Dications

Por Brendle, James J., Outlaw, Abram, Kumar, Arvind, Boykin, David W., Patrick, Donald A., Tidwell, Richard R., Werbovetz, Karl A.
Publicado em 2002

Phenotypic Drug Discovery for Human African Trypanosomiasis: A Powerful Approach

Por Buckner, Frederick S., Buchynskyy, Andriy, Nagendar, Pendem, Patrick, Donald A., Gillespie, J. Robert, Herbst, Zackary, Tidwell, Richard R., Gelb, Michael H.
Publicado no Trop Med Infect Dis (2020)

Accumulation and Intracellular Distribution of Antitrypanosomal Diamidine Compounds DB75 and DB820 in African Trypanosomes

Por Mathis, Amanda M., Holman, Jacqueline L., Sturk, Lisa M., Ismail, Mohamed A., Boykin, David W., Tidwell, Richard R., Hall, James Edwin
Publicado em 2006

A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a “Highly Twisted” Benzimidazole-Diamidine

Por Goodwin, Kristie D., Lewis, Mark A., Tanious, Farial A., Tidwell, Richard R., Wilson, W. David, Georgiadis, Millie M., Long, Eric C.
Publicado em 2006