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New Treatment Option for Second-Stage African Sleeping Sickness: In Vitro and In Vivo Efficacy of Aza Analogs of DB289

African sleeping sickness is a fatal parasitic disease, and all drugs currently in use for treatment have strong liabilities. It is essential to find new, effective, and less toxic drugs, ideally with oral application, to control the disease. In this study, the aromatic diamidine DB75 (furamidine) a...

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Detalhes bibliográficos
Main Authors: Wenzler, Tanja, Boykin, David W., Ismail, Mohamed A., Hall, James Edwin, Tidwell, Richard R., Brun, Reto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764217/
https://ncbi.nlm.nih.gov/pubmed/19620327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00225-09
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