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Designed compounds for recognition of ten base pairs of DNA with two AT binding sites

Short AT base pair sequences that are separated by a small number of GCs are common in eukaryotic parasite genomes. Cell-permeable compounds that bind effectively and selectively to such sequences present an attractive therapeutic approach. Compounds with linked, one or two amidine-benzimidazole-phe...

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Detalles Bibliográficos
Main Authors: Liu, Yang, Chai, Yun, Kumar, Arvind, Tidwell, Richard R., Boykin, David W., Wilson, W. David
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526804/
https://ncbi.nlm.nih.gov/pubmed/22369366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211628j
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