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Understanding Mixed Sequence DNA Recognition by Novel Designed Compounds: The Kinetic and Thermodynamic Behavior of Azabenzimidazole Diamidines

[Image: see text] Sequence-specific recognition of DNA by small organic molecules offers a potentially effective approach for the external regulation of gene expression and is an important goal in cell biochemistry. Rational design of compounds from established modules can potentially yield compound...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Paul, Ananya, Chai, Yun, Boykin, David W., Wilson, W. David
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303320/
https://ncbi.nlm.nih.gov/pubmed/25495885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500989r
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