The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine

[Image: see text] DB1255 is a symmetrical diamidinophenyl-dithiophene that exhibits cellular activity by binding to DNA and inhibiting binding of ERG, an ETS family transcription factor that is commonly overexpressed or translocated in leukemia and prostate cancer [Nhili, R., Peixoto, P., Depauw, S....

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Bibliographic Details
Main Authors: Munde, Manoj, Kumar, Arvind, Peixoto, Paul, Depauw, Sabine, Ismail, Mohamed A., Farahat, Abdelbasset A., Paul, Ananya, Say, Martial V., David-Cordonnier, Marie-Hélène, Boykin, David W., Wilson, W. David
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985535/
https://ncbi.nlm.nih.gov/pubmed/24495039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401582t
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