A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a “Highly Twisted” Benzimidazole-Diamidine

Míreanna Comhchosúla

• Unusually Strong Binding to the DNA Minor Groove by a Highly Twisted Benzimidazole-Diphenylether: Induced Fit and Bound Water
  le: Tanious, Farial A., et al.
  Foilsithe: (2007)
• Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library
  le: Glass, LaTeca S., et al.
  Foilsithe: (2010)
• Crystal structure of DNA-bound Co(III)·bleomycin B(2): Insights on intercalation and minor groove binding
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  Foilsithe: (2008)
• High-Resolution Crystal Structures Reveal Plasticity in the Metal Binding Site of Apurinic/Apyrimidinic Endonuclease I
  le: He, Hongzhen, et al.
  Foilsithe: (2014)
• A host–guest approach for determining drug–DNA interactions: an example using netropsin
  le: Goodwin, Kristie D., et al.
  Foilsithe: (2005)