Functional consequences of EpCam mutation in mice and men

Por Mueller, James L., McGeough, Matthew D., Peña, Carla A., Sivagnanam, Mamata
Publicado em 2013

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

Por Brydges, Susannah D., Broderick, Lori, McGeough, Matthew D., Pena, Carla A., Mueller, James L., Hoffman, Hal M.
Publicado em 2013

Interleukin-6 is a Marker of Inflammation with No Direct Role in Inflammasome-Mediated Mouse Models()

Por McGeough, Matthew D., Pena, Carla A., Mueller, James L., Pociask, Derek A., Broderick, Lori, Hoffman, Hal M., Brydges, Susannah D.
Publicado em 2012

Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction

Por Kozan, Philip A., McGeough, Matthew D., Peña, Carla A., Mueller, James L., Barrett, Kim E., Marchelletta, Ronald R., Sivagnanam, Mamata
Publicado no J Mol Med (Berl) (2014)

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis

Por Wree, Alexander, Eguchi, Akiko, McGeough, Matthew D., Pena, Carla A., Johnson, Casey D., Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
Publicado em 2014

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

Por Wree, Alexander, McGeough, Matthew D., Peña, Carla A., Schlattjan, Martin, Li, Hongying, Inzaugarat, Maria Eugenia, Messer, Karen, Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
Publicado no J Mol Med (Berl) (2014)

TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies

Por McGeough, Matthew D., Wree, Alexander, Inzaugarat, Maria E., Haimovich, Ariela, Johnson, Casey D., Peña, Carla A., Goldbach-Mansky, Raphaela, Broderick, Lori, Feldstein, Ariel E., Hoffman, Hal M.
Publicado no J Clin Invest (2017)

Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart

Por Toldo, Stefano, Mezzaroma, Eleonora, McGeough, Matthew D., Peña, Carla A., Marchetti, Carlo, Sonnino, Chiara, Van Tassell, Benjamin W., Salloum, Fadi N., Voelkel, Norbert F., Hoffman, Hal M., Abbate, Antonio
Publicado no Cardiovasc Res (2015)

NLRP3 inflammasome driven liver injury and fibrosis: roles of IL- 17 and TNF

Por Wree, Alexander, McGeough, Matthew D., Inzaugarat, Maria Eugenia, Eguchi, Akiko, Schuster, Susanne, Johnson, Casey D., Peña, Carla A., Geisler, Lukas J., Papouchado, Bettina G, Hoffman, Hal M., Feldstein, Ariel E.
Publicado no Hepatology (2017)

ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma

Por Miller, Marina, Rosenthal, Peter, Beppu, Andrew, Mueller, James L, Hoffman, Hal M., Tam, Arvin B., Doherty, Taylor A., McGeough, Matthew D., Pena, Carla A, Suzukawa, Maho, Niwa, Maho, Broide, David H.
Publicado em 2014

NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms

Por Qu, Chao, Bonar, Sheri L., Hickman-Brecks, Cynthia L., Abu-Amer, Samer, McGeough, Matthew D., Peña, Carla A., Broderick, Lori, Yang, Chang, Grimston, Susan K., Kading, Jacqueline, Abu-Amer, Yousef, Novack, Deborah V., Hoffman, Hal M., Civitelli, Roberto, Mbalaviele, Gabriel
Publicado no FASEB J (2015)

Animal Models of Inflammasomopathies Reveal Roles for Innate but not Adaptive Immunity

Por Brydges, Susannah D, Mueller, James L, McGeough, Matthew D, Pena, Carla A, Misaghi, Amirhossein, Gandhi, Chhavi, Putnam, Chris D, Boyle, David L, Firestein, Gary S, Horner, Anthony A, Soroosh, Pejman, Watford, Wendy T, O’Shea, John J, Kastner, Daniel L, Hoffman, Hal M
Publicado em 2009