Unexpected pieces to the senescence puzzle

af Cichowski, Karen, Hahn, William C.
Udgivet 2008

Identifying the ubiquitin ligase complex that regulates the NF1 tumor suppressor and Ras

af Hollstein, Pablo E., Cichowski, Karen
Udgivet 2013

SPRED proteins provide a NF-ty link to Ras suppression

af McClatchey, Andrea I., Cichowski, Karen
Udgivet 2012

Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is

af Liao, Sida, Maertens, Ophélia, Cichowski, Karen, Elledge, Stephen J.
Udgivet i Genes Dev (2018)

Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor

af Cichowski, Karen, Santiago, Sabrina, Jardim, Melanie, Johnson, Bryan W., Jacks, Tyler
Udgivet 2003

The NF1 tumor suppressor critically regulates TSC2 and mTOR

af Johannessen, Cory M., Reczek, Elizabeth E., James, Marianne F., Brems, Hilde, Legius, Eric, Cichowski, Karen
Udgivet 2005

Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers

af Malone, Clare F., Fromm, Jody A., Maertens, Ophélia, DeRaedt, Thomas, Ingraham, Rachel, Cichowski, Karen
Udgivet i Cancer Discov (2014)

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

af Johnson, Leisa, Greenbaum, Doron, Cichowski, Karen, Mercer, Kim, Murphy, Elizabeth, Schmitt, Eric, Bronson, Roderick T., Umanoff, Heywood, Edelmann, Windfried, Kucherlapati, Raju, Jacks, Tyler
Udgivet 1997

ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

af Engelman, Jeffrey A., Jänne, Pasi A., Mermel, Craig, Pearlberg, Joseph, Mukohara, Toru, Fleet, Christina, Cichowski, Karen, Johnson, Bruce E., Cantley, Lewis C.
Udgivet 2005

Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers

af Lock, Rebecca, Ingraham, Rachel, Maertens, Ophélia, Miller, Abigail L., Weledji, Nelly, Legius, Eric, Konicek, Bruce M., Yan, Sau-Chi B., Graff, Jeremy R., Cichowski, Karen
Udgivet i J Clin Invest (2016)

A negative feedback signaling network underlies oncogene-induced senescence

af Courtois-Cox, Stéphanie, Genther Williams, Sybil M., Reczek, Elizabeth E., Johnson, Bryan W., McGillicuddy, Lauren T., Johannessen, Cory M., Hollstein, Pablo, MacCollin, Mia, Cichowski, Karen
Udgivet 2006

The RasGAP Gene, RASAL2, is a Tumor and Metastasis Suppressor

af McLaughlin, Sara Koenig, Olsen, Sarah Naomi, Dake, Benjamin, De Raedt, Thomas, Lim, Elgene, Bronson, Roderick Terry, Beroukhim, Rameen, Polyak, Kornelia, Brown, Myles, Kuperwasser, Charlotte, Cichowski, Karen
Udgivet 2013

mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors

af Malone, Clare F., Emerson, Chloe, Ingraham, Rachel, Barbosa, William, Guerra, Stephanie, Yoon, Haejin, Liu, Lin L., Michor, Franziska, Haigis, Marcia, Macleod, Kay F., Maertens, Ophélia, Cichowski, Karen
Udgivet i Cancer Discov (2017)

Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

af Zhang, Yang, Guillermier, Christelle, De Raedt, Thomas, Cox, Andrew G., Maertens, Ophelia, Yimlamai, Dean, Lun, Mingyue, Whitney, Adam, Maas, Richard L., Goessling, Wolfram, Cichowski, Karen, Steinhauser, Matthew L.
Udgivet i iScience (2020)

Elucidating distinct roles for NF1 in melanomagenesis

af Maertens, Ophélia, Johnson, Bryan, Hollstein, Pablo, Frederick, Dennie T., Cooper, Zachary A., Messiaen, Ludwine, Bronson, Roderick T., McMahon, Martin, Granter, Scott, Flaherty, Keith, Wargo, Jennifer A., Marais, Richard, Cichowski, Karen
Udgivet 2012

Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

af Takahashi, Nobuaki, Chen, Hsing-Yu, Harris, Isaac S., Stover, Daniel G., Selfors, Laura M., Bronson, Roderick T., Deraedt, Thomas, Cichowski, Karen, Welm, Alana L., Mori, Yasuo, Mills, Gordon B., Brugge, Joan S.
Udgivet i Cancer Cell (2018)

IL1α antagonizes IL1β and promotes adaptive immune rejection of malignant tumors

af Tian, Tian, Lofftus, Serena, Pan, Youdong, Stingley, Claire A, King, Sandra L, Zhao, Jingxia, Pan, Timothy Y, Lock, Rebecca, Marglous, Jacob W, Liu, Kevin, Widlund, Hans R, Fuhlbrigge, Robert, Cichowski, Karen, Kupper, Thomas S
Udgivet i Cancer Immunol Res (2020)

Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy

af Montero, Joan, Sarosiek, Kristopher A., DeAngelo, Joseph D., Maertens, Ophélia, Ryan, Jeremy, Ercan, Dalia, Piao, Huiying, Horowitz, Neil S., Berkowitz, Ross S., Matulonis, Ursula, Jänne, Pasi A., Amrein, Philip C., Cichowski, Karen, Drapkin, Ronny, Letai, Anthony
Udgivet i Cell (2015)

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies

af Maertens, Ophélia, McCurrach, Mila E., Braun, Benjamin S., De Raedt, Thomas, Epstein, Inbal, Huang, Tannie Q., Lauchle, Jennifer O., Lee, Hyerim, Wu, Jianqiang, Cripe, Timothy P., Clapp, D. Wade, Ratner, Nancy, Shannon, Kevin, Cichowski, Karen
Udgivet i Cancer Res (2017)

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-κB

af Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K., Reczek, Elizabeth E., De Raedt, Thomas, Guney, Isil, Strochlic, David E., Laura, E., Beroukhim, Rameen, Bronson, Roderick T., Ryeom, Sandra, Hahn, William C., Loda, Massimo, Cichowski, Karen
Udgivet 2010