Resultados da pesquisa - brain ((tumor 1) or (tumor rna)) treat

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221

Endocan as a prognostic biomarker of triple-negative breast cancer

Endocan as a prognostic biomarker of triple-negative breast cancer

Por Sagara, Atsunobu, Igarashi, Katsuhide, Otsuka, Maky, Kodama, Akihiro, Yamashita, Mutsumi, Sugiura, Rei, Karasawa, Takeshi, Arakawa, Kazuhiko, Narita, Michiko, Kuzumaki, Naoko, Narita, Minoru, Kato, Yoshinori
Publicado no Breast Cancer Res Treat (2016)

“... were more rapid than those of MDA-MB-231. RNA sequencing identified ESM1 as a gene that was expressed...”
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222

Molecular and clinical characterization of Galectin‐9 in glioma through 1,027 samples

Molecular and clinical characterization of Galectin‐9 in glioma through 1,027 samples

Por Yuan, Feng, Ming, Haolang, Wang, Yingshuai, Yang, Yihan, Yi, Li, Li, Tao, Ma, Haiwen, Tong, Luqing, Zhang, Liang, Liu, Peidong, Li, Jiabo, Lin, Yu, Yu, Shengping, Ren, Bingcheng, Yang, Xuejun
Publicado no J Cell Physiol (2019)

“.... In this study, first, we methodically gathered 1,027 glioma patients with RNA‐seq and 986 patients with survival...”
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223

STEM-03. WAVE1 KNOCKDOWN ENHANCES THE ANTITUMOR EFFICACY IN PRIMARY GLIOBLASTOMA NEUROSPHERES

STEM-03. WAVE1 KNOCKDOWN ENHANCES THE ANTITUMOR EFFICACY IN PRIMARY GLIOBLASTOMA NEUROSPHERES

Por Namagiri, Sriya, Thammegowda, Shilpa, Sur, Hannah, Vézina, Amélie, Chowdhury, Ashis, Maric, Dragan, Gangaplara, Arunakumar, Edwards, Nancy, Jackson, Sadhana, Ray-Chaudhury, Abhik, Heiss, John, Banasavadi-Siddegowda, Yeshavanth Kumar
Publicado no Neuro Oncol (2020)

“.... METHODS: Expression of WAVE1 in normal brain and GBM tumor specimens was assessed by immunohistochemistry...”
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224

ABC Transporter Inhibition Plus Dexamethasone Enhances the Efficacy of Convection Enhanced Delivery in H3.3K27M Mutant Diffuse Intrinsic Pontine Glioma

ABC Transporter Inhibition Plus Dexamethasone Enhances the Efficacy of Convection Enhanced Delivery in H3.3K27M Mutant Diffuse Intrinsic Pontine Glioma

Por Tsvankin, Vadim, Hashizume, Rintaro, Katagi, Hiroaki, Herndon, James E, Lascola, Christopher, Venkatraman, Talaignair N, Picard, Daniel, Burrus, Brainard, Becher, Oren J, Thompson, Eric M
Publicado no Neurosurgery (2020)

“... kinase inhibitor, in a transgenic H3.3K27M mutant murine model was assessed. mRNA expression of ABCB1 (p...”
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225

PATH-55. MUTATIONS OF H3.3 AND H3.1 IN A LARGE COHORT OF GLIOMAS

PATH-55. MUTATIONS OF H3.3 AND H3.1 IN A LARGE COHORT OF GLIOMAS

Por Sumrall, Ashley, Mittal, Sandeep, Phuphanich, Surasak, Heimberger, Amy, Eschbacher, Jenny, Korn, Michael, Gatalica, Zoran, Pandey, Manjari, Xiu, Joanne
Publicado no Neuro Oncol (2019)

“... mutations were identified. A HIST1H3B-K27M was detected in a tumor from the brain stem. H3 mutations were...”
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226

IMMU-13. CRISPR/CAS9-MEDIATED SILENCING OF SHP-1 SIGNIFICANTLY ENHANCES THE ANTI-GLIOMA ACTIVITY OF IL-13Rα2 CAR T CELLS

IMMU-13. CRISPR/CAS9-MEDIATED SILENCING OF SHP-1 SIGNIFICANTLY ENHANCES THE ANTI-GLIOMA ACTIVITY OF IL-13Rα2 CAR T CELLS

Por Petersen, Christopher, Bell, Matthew, Houke, Haley, Yi, Zongzhen, Gottschalk, Stephen, Krenciute, Giedre
Publicado no Neuro Oncol (2019)

“... IL-13Rα2.SHP-1 KO CAR T cells by electroporation of IL13Rα2-CARs with SHP-1 targeted Cas9-sgRNA...”
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227

Protective effect of picolinic acid on mice intracerebrally infected with lethal doses of Candida albicans.

Protective effect of picolinic acid on mice intracerebrally infected with lethal doses of Candida albicans.

Por Blasi, E, Mazzolla, R, Pitzurra, L, Barluzzi, R, Bistoni, F
Publicado em 1993

“... of brain tissues demonstrates that mRNA levels specific for tumor necrosis factor and interleukin 1...”
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228

An in vivo immunotherapy screen of costimulatory molecules identifies Fc-OX40L as a potent reagent for the treatment of established murine gliomas

An in vivo immunotherapy screen of costimulatory molecules identifies Fc-OX40L as a potent reagent for the treatment of established murine gliomas

Por Murphy, Katherine A., Lechner, Melissa G., Popescu, Flavia E., Bedi, Jessica, Decker, Stacy A., Hu, Peisheng, Erickson, Jami R., O’Sullivan, M. Gerard, Swier, Lauryn, Salazar, Andres M., Olin, Michael R., Epstein, Alan L., Ohlfest, John R.
Publicado em 2012

“... portion of human immunoglobulin. Lymphocytes and mRNA were purified from the brain tumor site for immune...”
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229

CSIG-11. TARGETING PD-L1 IN GLIOBLASTOMA USING NANOPARTICLE-BASED GENE EDITING

CSIG-11. TARGETING PD-L1 IN GLIOBLASTOMA USING NANOPARTICLE-BASED GENE EDITING

Por Tran, An, Fierro, Javier, Dou, Huanyu
Publicado no Neuro Oncol (2020)

“...Glioblastoma multiforme (GBM) is an astrocyte derived brain tumor with very poor prognosis, usually...”
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230

Downregulation of Pygopus 2 inhibits vascular mimicry in glioma U251 cells by suppressing the canonical Wnt signaling pathway

Downregulation of Pygopus 2 inhibits vascular mimicry in glioma U251 cells by suppressing the canonical Wnt signaling pathway

Por WANG, HAIDONG, FU, JIANHUA, XU, DIANSHUANG, XU, WEIWEI, WANG, SHIYONG, ZHANG, LIU, XIANG, YONGSHENG
Publicado no Oncol Lett (2016)

“...Gliomas are the most common type of malignant primary brain tumor, and the Wnt signaling pathway...”
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231

PDTM-11. YAP1 IS NECESSARY FOR TUMORIGENESIS AND CANCER STEM CELLMAINTENANCE IN SHH-INDUCED MEDULLOBLASTOMAS

PDTM-11. YAP1 IS NECESSARY FOR TUMORIGENESIS AND CANCER STEM CELLMAINTENANCE IN SHH-INDUCED MEDULLOBLASTOMAS

Por Natarajan, Sivaraman, George, Joshy, Olson, James M, Camargo, Fernando, Yun, Kyuson
Publicado no Neuro Oncol (2017)

“... tumor patients to preserve normal brain development and function. We propose that SHH medulloblastomas...”
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232

MEDU-39. YAP1 IS NECESSARY FOR TUMORIGENESIS AND CANCER STEM CELL MAINTENANCE IN SHH-INDUCED MEDULLOBLASTOMAS

MEDU-39. YAP1 IS NECESSARY FOR TUMORIGENESIS AND CANCER STEM CELL MAINTENANCE IN SHH-INDUCED MEDULLOBLASTOMAS

Por Natarajan, Sivaraman, George, Joshy, Camargo, Fernando, Yun, Kyuson
Publicado no Neuro Oncol (2017)

“...Treatments with minimal adverse effects are particularly important for pediatric brain tumor...”
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233

Breast cancer resistant protein (BCRP/ABCG(2)) localizes to the nucleus in glioblastoma multiforme cells

Breast cancer resistant protein (BCRP/ABCG(2)) localizes to the nucleus in glioblastoma multiforme cells

Por Bhatia, Prateek, Bernier, Michel, Sanghvi, Mitesh, Moaddel, Ruin, Schwarting, Roland, Ramamoorthy, Anuradha, Wainer, Irving W.
Publicado em 2012

“... was found in a subpopulation of tumor cells in a human brain GBM biopsy. 3. Mitoxantrone cytotoxicity...”
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234

Knockdown of AKT3 (PKB
γ) and PI3KCA Suppresses Cell Viability and Proliferation and Induces the Apoptosis of Glioblastoma Multiforme T98G Cells

Knockdown of AKT3 (PKB γ) and PI3KCA Suppresses Cell Viability and Proliferation and Induces the Apoptosis of Glioblastoma Multiforme T98G Cells

Por Paul-Samojedny, Monika, Suchanek, Renata, Borkowska, Paulina, Pudełko, Adam, Owczarek, Aleksander, Kowalczyk, Małgorzata, Machnik, Grzegorz, Fila-Daniłow, Anna, Kowalski, Jan
Publicado em 2014

“...Glioblastoma multiforme (GBM) is the most malignant and invasive human brain tumor...”
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235

PD-L1 Inhibitor Regulates the miR-33a-5p/PTEN Signaling Pathway and Can Be Targeted to Sensitize Glioblastomas to Radiation

PD-L1 Inhibitor Regulates the miR-33a-5p/PTEN Signaling Pathway and Can Be Targeted to Sensitize Glioblastomas to Radiation

Por Xia, Wenzheng, Zhu, Jin, Tang, Yinda, Wang, Xueyi, Wei, Xiangyu, Zheng, Xuan, Hou, Meng, Li, Shiting
Publicado no Front Oncol (2020)

“...Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Ionizing radiation (IR...”
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236

Chronic NMDA Administration Increases Neuroinflammatory Markers in Rat Frontal Cortex: Cross-Talk Between Excitotoxicity and Neuroinflammation

Chronic NMDA Administration Increases Neuroinflammatory Markers in Rat Frontal Cortex: Cross-Talk Between Excitotoxicity and Neuroinflammation

Por Chang, Yunyoung C., Kim, Hyung-Wook, Rapoport, Stanley I., Rao, Jagadeesh S.
Publicado em 2008

“... brain markers of neuroinflammation, NMDA (25 mg/kg i.p.) or vehicle (1 ml saline/kg i...”
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237

Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

Por Yinfang Wang, Yanli Hou, Weiwei Zhang, Angel A. Alvarez, Yongrui Bai, Bo Hu, Shi-Yuan Cheng, Kun Yang, Yanxin Li, Haizhong Feng
Publicado em 2019-04-01

Assuntos: “...G0/G1 switch gene 2 (G0S2)...”
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238

Estrogen receptor variant ER‐α36 promotes tamoxifen agonist activity in glioblastoma cells

Estrogen receptor variant ER‐α36 promotes tamoxifen agonist activity in glioblastoma cells

Por Qu, Chao, Ma, Jingyun, Zhang, Yejun, Han, Chao, Huang, Liang, Shen, Liming, Li, Hongyan, Wang, Xiaobo, Liu, Jing, Zou, Wei
Publicado no Cancer Sci (2019)

“...Glioblastoma (GBM) is a highly infiltrative and malignant primary brain tumor. Despite aggressive...”
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239

Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells

Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells

Por Lee, Jong-Eun, Yoon, Sung Sik, Moon, Eun-Yi
Publicado no Biomol Ther (Seoul) (2019)

“... using small interference RNA (siRNA) of Atg5 or Beclin1. Therefore, curcumin-mediated tumor cell death...”
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240

TNF-α receptor 1 knockdown in the subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats

TNF-α receptor 1 knockdown in the subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats

Por Yu, Yang, Wei, Shun-Guang, Weiss, Robert M., Felder, Robert B.
Publicado no Am J Physiol Heart Circ Physiol (2017)

“...-operated rats. In HF rats treated with TNFR1 shRNA, TNFR1 was reduced in the SFO but not paraventricular...”
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